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Nanotechnology in Pharmaceutical Research- Magnetic fields drive Paclitaxel -loaded nanoparticles to reduce blood vessel blockages.
Dr.Shruti Bhat, Leader Pharmaceutical R&D and Expert in hiTech formulation development for over 35 different therapeutic class of drugs moeities, brings to you some highlights from current pharma and clinical research news, views and data.
Scientists and engineers have used uniform magnetic fields to drive iron-bearing nanoparticles to metal stents in injured blood vessels, where the particles deliver a drug payload that successfully prevents blockages in those vessels.
In this animal study, the novel technique achieved better results at a lower dose than conventional non-magnetic stent therapy.
Conducted in cell cultures and rats, the research is the latest in a series of studies at The Children's Hospital of Philadelphia demonstrating the feasibility of magnetically guided nanoparticles as a new delivery platform for a variety of possible therapeutic cargos: DNA, cells and drugs. The findings may set the stage for a new medical tool, called vascular magnetic intervention....
More at http://www.pharm-education.com/2010/04/nanotechnology-in-pharmaceutical.html
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